SECTION ONE: Education, Research Experience, Awards and Scholarships, Memberships in Professional Societies
SECTION TWO: Ph.D. Thesis, Publications
SECTION THREE: Abstracts and Presentations
SECTION FOUR:  Grants Received, Grants Pending
SECTION FIVE:  University Governance, Courses Taught, Undergraduate Research Supervised, Graduate Research Supervised, Graduate Research (Service on Advisory, Examining and Reading Committees, Postdoctoral Research Associates

1985  B.Sc. (Honors, Engineering Chemistry)
    Faculty of Applied Science, Queen's University at Kingston, Ontario, Canada
1990  Ph.D. (Computational and Carbohydrate Chemistry)
    School of Graduate Studies and Research, Queen's University
1991-1992 Associate Member Linacre College, University of Oxford, United Kingdom
1993  Associate Member Corpus Christi College, University of Oxford, United Kingdom

Research Experience:

1985-1990 Teaching Assistant, Department of Chemistry, Queen's University, Kingston, Ontario, Canada
1990  Teaching Assistant, ACS Short Course in Molecular Modeling, The University of North Carolina
1990-1991 Postdoctoral Fellow, Laboratory for Molecular Modeling, The University of North Carolina
1991-1994 Postdoctoral Fellow, Glycobiology Institute, The University of Oxford, United Kingdom
1994-1995 Term Scientist, Institute for Biological Sciences, National Research Council of Canada, Ottawa, Canada
1995-Present Assistant Professor, Complex Carbohydrate Research Center and Department of Biochemistry and Molecular Biology, The University of Georgia, Athens
1996-Present Member, Computational Center for Molecular Structure and Design, Department of Chemistry, The University of Georgia, Athens

Awards and Scholarships:

1985-1986 Queen's University Graduate Fellowship
1986-1987 Province of Ontario Graduate Studies Scholarship
1987-1990 National Sciences and Engineering Research Council of Canada, 
NSERC Graduate Scholarship
1990-1992 Natural Sciences and Engineering Research Council of Canada, 
NSERC Postdoctoral Fellowship
1992 University of Oxford, Lockey Bequest
1999 Member of Group Study Exchange Program to Argentina, Athens West Rotary Club

Memberships in Professional Societies:

1982-1991 Member, Chemical Institute of Canada
1990-Present Member, American Chemical Society 
1991-Present Member, Royal Society of Chemistry
1999-Present Member, Society for Glycobiology

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1990  An investigation of the structural and electronic properties of hexuloses: Toward an understanding 
         of the molecular properties responsible for sweetness. 
 

Publications:

Woods, R.J., V.H. Smith, Jr., W.A. Szarek, and A. Farazdel.  1987.  Ab initio LCAO-MO calculations on a-D-glucopyranose, b-D-fructopyranose, and their thiopyranoid-ring analogues. Appllication to a theory of sweetness. J. Chem. Soc., Chem. Commun. 937-939.

Woods, R.J., K.A. Watson, F. Fortier, and W.A. Szarek.  1989.  The conformation of 6-thio-b-D-fructopyranose in the crystalline state.  Carbohydrate Res. 193: 1-7.

Woods, R.J., M. Khalil, W. Pell, S.H. Moffat, and V.H. Smith, Jr.  1990.  Derivation of net atomic charges from molecular electrostatic potentials.  J. Comput. Chem. 11: 297-310.

Khalil, M., R.J. Woods, D.F. Weaver, and V.H. Smith, Jr.  An examination of intermolecular and intramolecular hydrogen bonding in biomolecules by AM1 and MNDO/M semiempirical methodologies.  J. Comput. Chem. 12: 584-593.

Woods, R.J., W.A. Szarek, and V.H. Smith, Jr.  1990.  An investigation of the relationship between sweetness and intra-molecular hydrogen-bonding networks in hexuloses using the semi-empirical molecular orbital method, AM1.  J. Am. Chem. Soc. 112: 4732-4741.

Woods, R.J., W.A. Szarek, and V.H. Smith, Jr.  1991.  The proton affinities and deprotonation enthalpies of b-D-fructopyraonse and a-L-sorbopyranose: An examination using the semiempirical molecular orbital method, AM1. Can. J. Chem. 69: 1917-1928.

Woods, R.J., W.A. Szarek, and V.H. Smith, Jr.  1991.  A comparison of the semiempirical and ab initio methods for the study of structural features of relevance in carbohydrate chemistry.  J. Chem. Soc., Chem. Commun. 334-337.

Woods, R.J., C.W. Andrews, and J.P. Bowen.  1992.  A molecular mechanical investigation of the properties of oxocarbenium ions I. Parameter development. J. Am. Chem. Soc. 114: 850-858.

Woods, R.J., C.W. Andrews, and J.P. Bowen.  1992.  A molecular mechanical investigation of the properties of oxocarbenium ions. II. Application to glycoside hydrolysis. J. Am. Chem. Soc. 114: 859-864.

Edge, C.J., H.C. Joao, R.J. Woods, and M.R. Wormald.  1993.  The conformational effects of N-linked glycosylation.  Biochem. Soc. Trans. 21: 452-455.

Woods, R.J., C.J. Edge, M.R. Wormald, and R.A. Dwek.  1993.  GLYCAM_93: A generalized parameter set for molecular dynamics simulations of glycoproteins and oligosaccharides. Application to the structure and dynamics of a disaccharide related to oligomannose.  In: Complex Carbohydrates in Drug Research (K. Bock, H. Clausen, P. Krogsagaard-Larsen, and H. Kofod, eds.), Afred Benzon Symposium Number 36, pp. 15-26.  Munksgaard, Copenhagen.

Woods, R.J., B. Fraser-Reid, C.J. Edge, and R.A. Dwek.  1993.  The role of nonbonded interactions in determining the solution conformations of oligosaccharides.  In: Modeling the Hydrogen Bond (D. Smith, ed.), ACS Symposium Series 569. American Chemical Society, Washington, DC.

Woods, R.J., C.J. Edge, and R.A. Dwek.  1994.  Protein surface oligosaccharides and protein function. Nature, Struct. Biol. 1: 499-501.

Woods, R.J., R.A. Dwek, C.J. Edge, and B. Fraser-Reid.  1995.  Molecular mechanical and molecular dynamical simulations of glycoproteins and oligosaccharides. 1. GLYCAM_93 parameter development.  J. Phys. Chem. 99: 3832-3846.

Rudd, P.M., R.J. Woods, M.R. Wormald, G. Opdenakker, A.K. Downing, I.D. Campbell, and R.A. Dwek.  1995.  The effects of variable glycosylation on the functional activities of ribonuclease, plasminogen and tissue plasminogen activator.  Biochimica et Biophysica Acta 1248: 1-10.

Woods, R.J.  1995.  3Dimensional structures of oligosaccharides.  Curr. Opin. Struct. Biol. 5: 591-598.

Woods, R.J.  1996.  The application of molecular modeling techniques to the determination of oligosaccharide solution conformations.  In: Reviews in Computational Chemistry, Vol. 9 (K. Lipkowitz and D.B. Boyd, eds.), pp. 129-165.  VCH Publishers, New York.

Brisson, J.-R., S. Uhrinova, R.J. Woods, M. Van der Zwan, H.C. Jarrell, L.C. Paoletti, D.L. Kasper, and H.J. Jennings.  1997.  NMR and molecular dynamics studies of the conformational epitope of the type-III Group-B Streptococcus capsular polysaccharide and derivatives.  Biochemistry 36: 3278-3292. 

Woods, R.J.  1998.  Computational carbohydrate chemistry: What theoretical methods can tell us.  Glycoconj. J. 15: 209-216.

Woods, R.J., A. Pathiaseril, M.R. Wormald, C.J. Edge, and R.A. Dwek.  1998.  The high degree of internal flexibility observed for an oligomannose oligosaccharide does not alter the overall topology of the molecule.  Eur. J. Biochem. 258: 372-386.

Woods, R.J.  1998.  Carbohydrate force fields.  In: Encyclopedia of Computational Chemistry, Vol. 1 (P.V.R. Schleyer, N.L. Allinger, T. Clark, J. Gasteiger, P.A. Kollman, H.F. Schaefer III, P.R. Schreiner, eds.), pp. 220-233.  John Wiley & Sons, Chichester.

Pathiaseril, A. and R.J. Woods.  2000.  Relative energies of binding for antibody carbohydrate-antigen complexes computed from free energy simulations. J. Am. Chem. Soc. 122: 331-338.

Woods, R.J. and R. Chappelle.  2000.  RESP-partial charges for condensed phase MD simulations. J. Mol. Struct. (THEOCHEM).  In press.

Basma M, Reuhs BL, Glushka J, Woods RJ. 2000.  NMR and molecular dynamics studies of the capsular polysaccharide (K antigen) from Sinorhizobium meliloti strain NRG247.  Glycobiology  10(10):  119.

Ford MG, Woods, RJ.  2000.  Conformational analysis of galectin-1 ligands in the bound state.  Glycobiology 10(10):  55.

K.N. Kirschner and R.J. Woods. 2001. A Study of the Non-Bonded Forces in Water-Methanol Complexes.  J. Phys. Chem. A  105(16):  4150-4155.

Basma, M., D. Calgan, and T. Varnali, R.J. Woods. 2001. Ensemble-averaged atomic partial charges for carbohydrate simulations.  J. Comput. Chem.  22(110):  1125-1137.

Bukowski, R., L. Morris, R.J. Woods, and T. Weimar. 2001. Synthesis and conformational analysis of the T-antigen disaccharide.  Eur. J. Org. Chem. 14: 2697-2705.

Kirschner KN, Woods RJ.  2001.  Solvent interactions determine carbohydrate conformation.  PNAS 98 (19):  10541-10545. 

Clarke C, Woods RJ, Gluska J, Cooper A, Nutley MA, Boons GJ.  2001.  Involvement of water in carbohydrate-protein binding.  J. Am. Chem. Soc. 123 (49): 12238-12247.

Tempel W, Lipscomb LA, Rose JP, Woods RJ.  2001.  The xenograft antigen in complex with GS-1-B-4 lectin:  crystallization and preliminary X-ray analysis.  Acta Crystallogr., Sect D:  Biol. Crystallogr. 57: 1639-1642.

Tempel W, Tschampel S, Woods RJ.  2002.  The xenograft antigen bound to Griffonia simplicifolia Lectin 1-B4.  J. Biol. Chem.  277 (8): 6615-6621

Tempel W, Lipscomb LA, Rose JP, Woods RJ.  2001.  The xenograft antigen in complex with GS-1-B-4 lectin:  crystallization and preliminary X-ray analysis.  Acta Crystallogr., Sect D:  Biol. Crystallogr. 57: 1639-1642.

Tschampel SM and Woods RJ.  2003.  Quantifying the role of water in protein-carbohydrate interactions.  J. Phys. Chem. A  107 (43): 9175-9181

Ford MG, Weimar T, Kohli T, and Woods RJ.  2003.  Molecular dynamics simulations of galectin-1-oligosaccharide complexes reveal the molecular basis for ligand diversity.  Prot. Struct. Funct. Gen.   53 (2): 229-240

Corzana F, Motawia MS, Du Penhoat CH, Perez S, Tschampel SM, Woods RJ and Engelsen, SB.  2004.  A hydration study of (1->4) and (1->6) linked alpha-glucans by comparative 10 ns molecular dynamics simulations and 500-MHz NMR.   J. Comput. Chem.  25 (4): 573-586
 
 

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Weaver, D.F., R.J. Woods, and S. Wolfe.  1985.  "A molecular mechanics strategy for peptides."  68th Chemical Institute of Canada Conference, June.

Woods, R.J., V.H. Smith, W.A. Szarek, and A. Farazdel.  1985.  "The application of ab initio molecular orbital calculations to sugars."  5th International Conference on Quantum Chemistry, Montreal, Quebec, Canada, August.

Woods, R.J., V.H. Smith, W.A. Szarek, and A. Farazdel.  1987.  "Ab initio LCAO-MO calculations on a-D-glucopyranose, b-D-fructopyranose and their thiopyranoid ring analogues."  70th Canadian Chemical Conference, Sainte-Foy, Quebec, Canada, June.

Woods, R.J., V.H. Smith, W.A. Szarek, and A. Farazdel.  1987.  "Ab initio LCAO-MO calculations on a-D-glucopyranose, b-D-fructopyranose and their thiopyranoid ring analogues."  American Chemical Society/Canadian Institute of Chemistry, Toronto, Canada, August.

Woods, R.J., M. Khalil, W. Pell, S.H. Moffat, and V.H. Smith.  1988.  "Guage dependance in the derivation of net atomic charges from molecular electrostatic potentials."  Gordon Research Conference on Computational Chemistry, Plymouth, New Hampshire, July.

Woods, R.J., V.H. Smith, and W.A. Szarek.  1989.  "The relationship between sweetness and intra-molecular hydrogen-bonding networks in hexuloses using the semi-empirical molecular orbital method, AM1."  Canadian Theoretical Chemistry Meeting, Banff, June.

Woods, R.J., V.H. Smith, and W.A. Szarek.  1990.  Sweetness and Intra-molecular hydrogen-bonding networks in hexuloses: An application of semiempirical MO calculations."  2nd World Congress of Theoretical Organic Chemists, Toronto, Canada, July.

Woods, R.J., C.W. Andrews, and J.P. Bowen.  1990.  "A molecular mechanical investigation of the properties of oxocarbenium ions."  American Chemical Society Meeting, Washington, DC. 

Woods, R.J., A. Mele, and R.A. Dwek.  1991.  "A comparison of calculated and experimental one-bond 1H-13C coupling constants in glycosides."  Royal Society of Chemistry 10th International Meeting on NMR Spectroscopy, St. Andrews, Scotland, July.

Woods, R.J., A. Mele, C.J. Edge, and R.A. Dwek.  1992.  "Substituent effects on the conformation of N- and O-glycosidic linkages: Theoretical and experimental observations."  11th European Experimental NMR Conference, June.

Woods, R.J., B. Fraser-Reid, RA. Dwek, and C.J. Edge.  1993.  "Role of non-bonded interactions in determining solution conformations of oligosaccharides."  206th National Meeting of the American Chemical Society, Chicago, Illinois, August.

Woods, R.J., C.J. Edge, B. Fraser-Reid, and R.A. Dwek.  1994.  "Unrestrained MD simulations in oligosaccharide conformational analysis."  Gordon Research Conference on Computational Chemistry, New Hampton, New Hampshire, July.

Woods, R.J., C.J. Edge, B. Fraser-Reid, and R.A. Dwek.  1994.  "Unrestrained molecular dynamics simulations in oligosaccharide conformational analysis: application to Man9GlcNAc2OH."  17th International Carbohydrate Symposium, Ottawa, Canada, July.

Woods, R.J., C.J. Edge, and R.A. `Dwek.  1994.  "Implication of the conformations and dynamics of protein surface oligosaccharides in protein function."  3rd International Satellite Symposium on the Conformational Analysis of Carbohydrates and Protein/Carbohydrate Interactions, Val Morin, Quebec, Canada, July.

Woods, R.J.  1995.  "Application of molecular dynamics to the capsular polysaccharides of Group B Streptococcus."  Presentation to National Research Council of Canada, Ottawa, Canada, May.

Woods, R.J.  1996.  "The application of computational methods to carbohydrate antigen-antibody interactions."  Presentation to the National Research Council of Canada, Ottawa, Canada, June.

Pathiaseril, A. and R.J. Woods.  1996.  "Free-energy simulations of carbohydrate protein interactions." Gordon Research Conferences, "Computational Chemistry", New Hampshire, June 30-July 5.

Woods, R.J. and A. Pathiaseril.  1996.  "Free-energy simulations of carbohydrate antigen-antibody interactions."  XIIIth International Carbohydrate Symposium, Milan, Italy, July 21-26.

Woods, R.J.  1996.  "The application of molecular modeling techniques to the determination of oligosaccharide solution conformations".  Department of Chemistry, Georgia State University, Atlanta, Georgia, October 21.

Woods, R.J.  1997.  ?Computing binding free energies: Application to Salmonella-O-antigen-antibody interactions.?  Gordon Conference, ?Carbohydrate Chemistry?, Tilton, New Hampshire, June 22-27.

Woods, R.J.  1997.  Lecture Series:  "Methods in carbohydrate force field development".  Department of Physics & CNR-IAIF, Palermo, Italy, August 6-15.

Woods, R.J.  1997.  "Application of free energy simulations in the prediction of carbohydrate-protein binding energies".  Department of Chemistry, Hamburg University, and Medical University of Luebeck, Germany, August 19.

Woods, R.J.  1997.  "The design of carbohydrate-mimicking peptides".  The Charité Hospital, Berlin, Germany, August 26.

Woods, R.J.  1998.  "Force field development and application in carbohydrate modeling."  Department of Chemistry Colloquium Series, University of Georgia, February 10.

Woods, R.J.  1998.  "Carbohydrate Recognition and Mimicry In the Immune System."  Department of Chemistry, Clarke Atlanta University, February 13.

Woods, R.J.  1998.  "Structural Aspects of Carbohydrate Recognition and Mimicry."  Institute of Molecular Medicine and Genetics, Medical College of Georgia, March 5.

Woods, R.J.  1998.  "Computational and Experimental Analysis of Carbohydrate Recognition." Presentation to the National Research Council of Canada, Ottawa, Canada, April 29.

Woods, R.J., A. Pathiaseril, R. Chappelle, D. Calgan, and T. Varnali.  1998.  "Ensemble averaged atomic partial charges for carbohydrate simulations."  Gordon Conference, "Computational Chemistry", Tilton, New Hampshire, June 28-July 3.

Woods, R.J., A. Pathiaseril, R. Chappell, D. Calgan, and T. Varnali.  1998.  "Ensemble averaged atomic partial charges for carbohydrate simulations."  International Carbohydrate Symposium, San Diego, California, August 9-14.

Woods, R.J., L.C. Morris, A.D. Yang, and T. Weimar.  1999.  "Development of 2nd generation GLYCAM parameters and application in MD simulations of carbohydrate-protein complexes."  Gordon Conference, "Carbohydrates", Tilton, New Hampshire, June 20-25.

Woods, R.J.  1999.  "Computing carbohydrate-rotein binding affinities." Department of Biochemistry, University of Birmingham, United Kingdom, July 9.

Woods, R.J.  1999.  "Free energy simulations applied to carbohydrate-protein complexes."  Eurocarb X, Galway, Ireland, July 11-18.

Woods, R.J.  2000.  "Computational studies of bacterial polysaccharides - an explanation for the presence of a common sequence motif."  University of Tennessee, Knoxville, March 29.

Woods, R.J.  2000.  "Computational studies of bacterial polysaccharides - an explanation for the presence of a common sequence motif." Oak Ridge National Laboratory, March 30.

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Agency:  NIH (First Award); #5R29GM55230
Title:   Computational Analysis of Carbohydrate Antigenicity
Role in Project: Principal Investigator
Amount:  $105,725 (first year)
Period of Award: 03/01/97-02/28/02

Agency:  NATO
Title:   Kinetic and Thermodynamic Analysis of Carbohydrate Recognition
Role in Project: Co-principal Investigator
Amount:  $6,000 (first year)
Period of Award: 05/01/97-04/30/98

Agency:  Mizutani Foundation for Glycoscience
Title:   Carbohydrate Mimics Complexed with Their Protein Receptors
Role in Project: Principal Investigator
Amount:  ¥5,000,000 Yen (~US $42,000)
Period of Award: 04/01/98-03/31/99

Agency:  UGA, Program in Biological Resources and Biotechnology
Title:   The Development of Peptides for Application in Xenograft Transplantation
Role in Project: Co-principal Investigator (with Dr. L. Lipscomb)
Amount:  $67,790
Period of Award: 07/01/98-06/31/00

Agency:  National Institutes of Health, Grant # 1-P41-RR05351
Title:   A Resource Center for Biomedical Complex Carbohydrates
PI:   Peter Albersheim
Role on Project: PI for Project 1:  ?Development and application of computational methods 
   for carbohydrate modeling?
Amount:  $448,880
Project Period: 8/1/99-7/31/04

Grants Pending:

Agency:  National Institutes of Health
Title:   Oral Candidiasis: Antigen Structure and Vaccine Design
Role on Project: Principal Investigator
Amount:  $1,171,040
Period:   4 years

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1995-1998 Member, Campus Information Technology Forum
1995-Present Member, Research Computing Advisory Committee
1995-Present Member, Research Computing Subcommittee on Curriculum Development
1995-Present Member, Faculty Search Committees:  Leigh Ann Lipiscomb, Michael Terns, Jim 
     Omichinski/Pascale Legault, Geert-Jan Boons, Will York
1998 Member, BCMB Committee to review postgraduate oral and written examination policies 
1998-Present Member, Molecular Biosciences Graduate Program Working Committee

Courses Taught:

BCMB 8010, Advanced Biochemistry and Molecular Biology I, Fall 1995, Fall 1996, Fall 1997, Fall 1998 
CHEM 8340, Organic Spectroscopic Analysis, Winter 1995
BCMB 8020, Advanced Biochemistry and Molecular Biology II, Winter 1996, Spring 1998 
BCMB 8110, Advanced Topics in Protein Structure-Function Relationships, Spring 1996
CHEM 8200/BCMB 8200, Molecular Modeling and Structure Computations, Fall 1998, Fall 1999
BCMB 4110/6110, Physical Biochemistry, Fall 1998, Fall 1999
BCMB 8130, Advanced Topics in Glycobiology, Fall 1999

Undergraduate Research Supervised:

Steven Moffat, Summer 1988 and Fall 1988, Department of Chemistry, Queen's University
John Wilson, 1989, Senior Project, Department of Chemistry, Queen's University
Kevin Collins, Fall 1996-1997, Department of Biochemistry and Molecular Biology, University of Georgia
Katrina Redmond, Spring 1996-1997, Department of Biochemistry and Molecular Biology, University of Georgia
Ryan Chappelle, 1997-present, Department of Biochemistry and Molecular Biology, University of Georgia
Wendi Turnipseed, 1998, Department of Biochemistry and Molecular Biology, University of Georgia
Abraham Yang, 1998-present, Department of Biochemistry and Molecular Biology, University of Georgia
Wai-Kit Lo, 1998-1999, Department of Biochemistry, Harvard University, Cambridge, Massachusetts
David Lynch, 1999-Present, Department of Biochemistry and Molecular Biology, University of Georgia
Sundara 

Graduate Research Supervised:

Sarah Tschampel, Ph.D., Chemistry
Maral Basma, Ph.D., Chemistry
Brian Busch, Ph.D., Chemistry
Michael Ford, Ph.D., Biochemistry and Molecular Biology

Graduate Research (Service on Advisory, Examining, and Reading Committees):

Laura Morris, Ph.D., Chemistry
John Calhoun, Ph.D., Biochemistry and Molecular Biology
Jason Goldstein, Ph.D., Biochemistry and Molecular Biology
Daniel King, Ph.D., Chemistry
Rollin King, Ph.D., Chemistry (graduated)
Jin-Kyu Lee, Ph.D., Biochemistry and Molecular Biology (graduated)
Jianyun Lu, Ph.D., Chemistry (graduated)
Ruby Nagelkerke, Ph.D., Chemistry (Queen's University) (graduated)
Leslie Purvis, M.S., Chemistry (graduated)
Chandu Ramanathan, Ph.D., Pharmacy (graduated)
Matthew Renfrew, Ph.D., Biochemistry and Molecular Biology
Paul Simon, Ph.D., Biochemistry and Molecular Biology (graduated)
Alex Tracy, Ph.D. Biochemistry and Molecular Biology

Postdoctoral Research Associates:

Jorge Gonzalez Outeirino, Ph.D., University College, London, England

Renuka Kadirvelraj, Ph.D., Indian Institute of Science, Bangalore, India
Michael Cooney, Ph.D., Princeton
Karl Kirchner, Ph.D., University of Georgia
Ahammadunny Pathiaseril, Ph.D., University of Georgia
Wolfram Temple, Ph.D., University of Salford, United Kingdom

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